勒乐乐 发表于 2023-10-23 10:23:29

全国多地医院出现感染患者!这两种药完全无效

<div class="wx_rich_media_content" id="jsWxContainer"><p style='margin-bottom: 16px;' data-mpa-powered-by="yiban.io"><br></p><section data-tools="135编辑器" data-id="132139" style='outline: 0px; letter-spacing: 0.544px; font-family: system-ui, -apple-system, BlinkMacSystemFont, Arial, sans-serif;'><section style='margin: 10px auto;outline: 0px;'><section style='outline: 0px;border-width: 1px;border-style: solid;border-color: rgb(27, 98, 176);border-radius: 10px;overflow: hidden;'><section style='padding: 10px;outline: 0px;background-color: rgb(255, 255, 254);'><section data-width="100%" style='outline: 0px;width: 655px;'><p style='outline: 0px;line-height: 2em;'><span style='outline: 0px;letter-spacing: 2px;color: rgb(38, 38, 38);'><span style='outline: 0px;background-color: transparent;caret-color: red;font-size: 16px;'>近期,全国多地医院出现较多肺炎支原体感染患者,多以儿童为主。</span><span style='outline: 0px;background-color: transparent;font-size: 16px;caret-color: red;font-family: mp-quote, -apple-system-font, BlinkMacSystemFont, Arial, sans-serif;'>支原体肺炎是儿童常见的社区获得性肺炎,多发于秋冬季。但今年该肺炎提前来袭,且患者数量较往年明显增加。</span></span><span style='font-size: 16px;letter-spacing: 2px;'>肺炎支原体感染可引起上呼吸道感染,也可引起肺炎等下呼吸道感染,还可引起肺外并发症,如自身免疫性溶血性贫血等。</span></p><p style='letter-spacing: 0.578px; line-height: 1.75em;'><span style='font-size: 16px;letter-spacing: 2px;'><br></span></p><p style='letter-spacing: 0.578px; line-height: 1.75em;'><span style='font-size: 16px;letter-spacing: 2px;'>由于肺炎支原体没有细胞壁,大家所熟悉的<strong><span style='color: rgb(61, 170, 214);'>青霉素</span></strong>和<strong><span style='color: rgb(61, 170, 214);'>头孢</span></strong>,这类抗生素都是以细胞壁作为靶点,因此<strong><span style='color: rgb(61, 170, 214);'>对肺炎支原体完全无效</span></strong>。大环内酯类抗菌药物,如<strong><span style='color: rgb(61, 170, 214);'>罗红霉素</span></strong>、<strong><span style='color: rgb(61, 170, 214);'>阿奇霉素</span></strong>,目前为肺炎支原体感染的首选治疗药物。大家如果出现发热伴有剧烈咳嗽,应及时就诊,尽快查明病因,规范治疗,切忌自行盲目用药。</span></p></section><section data-width="100%" style='outline: 0px;width: 655px;'><p 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style='margin-left: 5px;outline: 0px;width: 5px;height: 10px;background-color: rgb(255, 255, 255);overflow: hidden;'><br style='outline: 0px;'></section><section style='margin-right: auto;margin-left: auto;outline: 0px;width: 18px;height: 6px;background-color: rgb(255, 255, 255);overflow: hidden;'><br style='outline: 0px;'></section></section></section><section style='outline: 0px;display: flex;justify-content: center;'><section style='outline: 0px;display: flex;align-items: center;'><section style='outline: 0px;flex-shrink: 0;z-index: 9;transform: translateY(-3px);'><section style='outline: 0px;width: 40px;height: 0px;overflow: hidden;'><br style='outline: 0px;'></section></section><section style='margin-left: -30px;padding: 3px;outline: 0px;background-color: rgb(45, 150, 127);border-radius: 25px;'><p style='padding: 1px 20px 1px 35px;outline: 0px;text-align: center;color: rgb(255, 255, 255);font-size: 16px;border-width: 1px;border-style: solid;border-color: rgb(210, 227, 223);border-radius: 25px;background-color: rgb(27, 98, 176);'><strong>支原体肺炎如何治疗?是否需要住院?</strong><strong data-brushtype="text" style='outline: 0px;letter-spacing: 0.544px;caret-color: red;'></strong></p></section></section></section><section style='padding: 8px 15px;outline: 0px;'><section data-width="100%" style='outline: 0px;width: 647px;'><span style='font-size: 16px;letter-spacing: 2px;'></span><br></section><section data-width="100%" style='outline: 0px;width: 647px;'><section style='letter-spacing: 0.578px;line-height: 1.75em;'><span style='letter-spacing: 1px;font-size: 16px;'>首先看支原体肺炎是轻症还是重症。轻症经过大环内酯类药物如阿奇霉素,克拉霉素,红霉素治疗一般均能控制病情,但体温正常后,咳嗽可能还会持续2周左右,胸片肺炎阴影基本均可吸收,可不复查胸片。</span></section><section style='letter-spacing: 0.578px;line-height: 1.75em;'><span style='letter-spacing: 1px;font-size: 16px;'><br></span></section><section style='letter-spacing: 0.578px;line-height: 1.75em;'><span style='font-size: 16px;'><strong><span style='letter-spacing: 1px;'>重症患者需要住院,通过大环内酯类药物静脉输液治疗。</span></strong><span style='letter-spacing: 1px;'>因我国耐药率高,之前若用过大环内酯类药物3天无效可更换为新型四环素类药物如米诺环素等,更严重的应用左氧氟沙星等药物。重者可能有混合病毒或者细菌感染,也需要加用相应的药物联合治疗。</span></span></section><p style='letter-spacing: 0.578px;line-height: 1.75em;'><span style='font-size: 16px;letter-spacing: 2px;'></span></p><p style='outline: 0px;line-height: 2em;'><br></p></section></section></section><section data-width="100%" style='outline: 0px;width: 677px;'><svg xmlns="http://www.w3.org/2000/svg" viewBox="0 0 579 26" style='display: block;'><path style='fill: #a0b1c5;fill-rule: evenodd;' d="M303,4717l579-1v26l-577.3-22.52Z" transform="translate(-303 -4716)"></path></svg></section></section></section><section data-role="paragraph" style='font-family: system-ui, -apple-system, BlinkMacSystemFont, Arial, sans-serif; letter-spacing: 0.544px; outline: 0px;'><section style='letter-spacing: 0.578px;line-height: 1.75em;'><br></section></section><section data-tools="135编辑器" data-id="129095" 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0px;'></section></section><section style='outline: 0px;'><section style='margin-right: auto;margin-left: auto;outline: 0px;width: 5px;height: 10px;background-color: rgb(255, 255, 255);overflow: hidden;'><br style='outline: 0px;'></section><section style='margin-right: auto;margin-left: auto;outline: 0px;width: 15px;height: 6px;background-color: rgb(255, 255, 255);overflow: hidden;'><br style='outline: 0px;'></section></section><section style='outline: 0px;'><section style='margin-right: auto;margin-left: auto;outline: 0px;width: 5px;height: 10px;background-color: rgb(255, 255, 255);overflow: hidden;'><br style='outline: 0px;'></section><section style='margin-right: auto;margin-left: auto;outline: 0px;width: 15px;height: 6px;background-color: rgb(255, 255, 255);overflow: hidden;'><br style='outline: 0px;'></section></section><section style='outline: 0px;'><section style='margin-left: 5px;outline: 0px;width: 5px;height: 10px;background-color: rgb(255, 255, 255);overflow: hidden;'><br style='outline: 0px;'></section><section style='margin-right: auto;margin-left: auto;outline: 0px;width: 18px;height: 6px;background-color: rgb(255, 255, 255);overflow: hidden;'><br style='outline: 0px;'></section></section></section><section style='outline: 0px;display: flex;justify-content: center;'><section style='outline: 0px;display: flex;align-items: center;'><section style='outline: 0px;flex-shrink: 0;z-index: 9;transform: translateY(-3px);'><section style='outline: 0px;width: 40px;height: 0px;overflow: hidden;'><br style='outline: 0px;'></section></section><section style='margin-left: -30px;padding: 3px;outline: 0px;background-color: rgb(45, 150, 127);border-radius: 25px;'><section style='padding: 1px 20px 1px 35px;outline: 0px;color: rgb(255, 255, 255);font-size: 16px;text-align: center;border-width: 1px;border-style: solid;border-color: rgb(210, 227, 223);border-radius: 25px;background-color: rgb(27, 98, 176);'><span style='outline: 0px;'><strong data-brushtype="text" style='outline: 0px;'>抗菌药物选择</strong></span></section></section></section></section><section style='padding: 8px 15px;outline: 0px;'><section data-width="100%" style='outline: 0px;width: 647px;'><br style='outline: 0px;'></section><section data-width="100%" style='outline: 0px;width: 647px;'><p style='outline: 0px;line-height: 2em;'><span style='outline: 0px;color: rgb(192, 0, 0);'><strong style='outline: 0px;'><span style='outline: 0px;letter-spacing: 2px;background-color: transparent;caret-color: red;font-size: 16px;'>大环内酯类抗菌药物</span></strong></span><span style='outline: 0px;letter-spacing: 2px;background-color: transparent;caret-color: red;font-size: 16px;color: rgb(38, 38, 38);'>是目前治疗儿童肺炎支原体肺炎的优选药物,其常见药物包括:</span><strong style='outline: 0px;'><span style='outline: 0px;letter-spacing: 2px;background-color: transparent;caret-color: red;font-size: 16px;color: rgb(38, 38, 38);'>红霉素、阿奇霉素、克拉霉素、罗红霉素等。</span></strong></p></section><section data-width="100%" style='outline: 0px;width: 647px;'><p style='outline: 0px;background-color: transparent;color: rgb(51, 51, 51);letter-spacing: 1.5px;caret-color: red;font-size: 16px;'><br style='outline: 0px;'></p></section><section data-width="100%" style='outline: 0px;width: 647px;'><p style='outline: 0px;line-height: 2em;'><span style='outline: 0px;background-color: transparent;caret-color: red;font-size: 16px;letter-spacing: 2px;color: rgb(38, 38, 38);'>因为阿奇霉素每日仅需1次用药,使用天数少,生物利用度高以及细胞内浓度高,依从性和耐受性均较高,已成为治疗优选。</span></p></section></section></section><section data-width="100%" style='outline: 0px;width: 677px;'><svg xmlns="http://www.w3.org/2000/svg" viewBox="0 0 579 26" style='display: block;'><path style='fill: #a0b1c5;fill-rule: evenodd;' d="M303,4717l579-1v26l-577.3-22.52Z" transform="translate(-303 -4716)"></path></svg></section></section></section><p style='outline: 0px; letter-spacing: 0.544px; font-family: system-ui, -apple-system, BlinkMacSystemFont, Arial, sans-serif;'><br></p><section data-tools="135编辑器" 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0px;'></section></section><section style='outline: 0px;'><section style='margin-right: auto;margin-left: auto;outline: 0px;width: 5px;height: 10px;background-color: rgb(255, 255, 255);overflow: hidden;'><br style='outline: 0px;'></section><section style='margin-right: auto;margin-left: auto;outline: 0px;width: 15px;height: 6px;background-color: rgb(255, 255, 255);overflow: hidden;'><br style='outline: 0px;'></section></section><section style='outline: 0px;'><section style='margin-right: auto;margin-left: auto;outline: 0px;width: 5px;height: 10px;background-color: rgb(255, 255, 255);overflow: hidden;'><br style='outline: 0px;'></section><section style='margin-right: auto;margin-left: auto;outline: 0px;width: 15px;height: 6px;background-color: rgb(255, 255, 255);overflow: hidden;'><br style='outline: 0px;'></section></section><section style='outline: 0px;'><section style='margin-right: auto;margin-left: auto;outline: 0px;width: 5px;height: 10px;background-color: rgb(255, 255, 255);overflow: hidden;'><br style='outline: 0px;'></section><section style='margin-right: auto;margin-left: auto;outline: 0px;width: 15px;height: 6px;background-color: rgb(255, 255, 255);overflow: hidden;'><br style='outline: 0px;'></section></section><section style='outline: 0px;'><section style='margin-right: auto;margin-left: auto;outline: 0px;width: 5px;height: 10px;background-color: rgb(255, 255, 255);overflow: hidden;'><br style='outline: 0px;'></section><section style='margin-right: auto;margin-left: auto;outline: 0px;width: 15px;height: 6px;background-color: rgb(255, 255, 255);overflow: hidden;'><br style='outline: 0px;'></section></section><section style='outline: 0px;'><section style='margin-right: auto;margin-left: auto;outline: 0px;width: 5px;height: 10px;background-color: rgb(255, 255, 255);overflow: hidden;'><br style='outline: 0px;'></section><section style='margin-right: auto;margin-left: auto;outline: 0px;width: 15px;height: 6px;background-color: rgb(255, 255, 255);overflow: hidden;'><br style='outline: 0px;'></section></section><section style='outline: 0px;'><section style='margin-right: auto;margin-left: auto;outline: 0px;width: 5px;height: 10px;background-color: rgb(255, 255, 255);overflow: hidden;'><br style='outline: 0px;'></section><section style='margin-right: auto;margin-left: auto;outline: 0px;width: 15px;height: 6px;background-color: rgb(255, 255, 255);overflow: hidden;'><br style='outline: 0px;'></section></section><section style='outline: 0px;'><section style='margin-right: auto;margin-left: auto;outline: 0px;width: 5px;height: 10px;background-color: rgb(255, 255, 255);overflow: hidden;'><br style='outline: 0px;'></section><section style='margin-right: auto;margin-left: auto;outline: 0px;width: 15px;height: 6px;background-color: rgb(255, 255, 255);overflow: hidden;'><br style='outline: 0px;'></section></section><section style='outline: 0px;'><section style='margin-left: 5px;outline: 0px;width: 5px;height: 10px;background-color: rgb(255, 255, 255);overflow: hidden;'><br style='outline: 0px;'></section><section style='margin-right: auto;margin-left: auto;outline: 0px;width: 18px;height: 6px;background-color: rgb(255, 255, 255);overflow: hidden;'><br style='outline: 0px;'></section></section></section><section style='outline: 0px;display: flex;justify-content: center;'><section style='outline: 0px;display: flex;align-items: center;'><section style='outline: 0px;flex-shrink: 0;z-index: 9;transform: translateY(-3px);'><section style='outline: 0px;width: 40px;height: 0px;overflow: hidden;'><br style='outline: 0px;'></section></section><section style='margin-left: -30px;padding: 3px;outline: 0px;background-color: rgb(45, 150, 127);border-radius: 25px;'><section style='padding: 1px 20px 1px 35px;outline: 0px;color: rgb(255, 255, 255);font-size: 16px;text-align: center;border-width: 1px;border-style: solid;border-color: rgb(210, 227, 223);border-radius: 25px;background-color: rgb(27, 98, 176);'><span style='outline: 0px;'><strong data-brushtype="text" style='outline: 0px;'>药物剂型选择</strong></span></section></section></section></section><section style='padding: 8px 15px;outline: 0px;'><p style='outline: 0px;width: 647px;'><br style='outline: 0px;'></p><p style='outline: 0px;width: 647px;line-height: 2em;'><span style='outline: 0px;letter-spacing: 2px;background-color: transparent;caret-color: red;font-size: 16px;color: rgb(38, 38, 38);font-family: Helvetica, Arial, sans-serif;'>根据《儿童肺炎支原体肺炎诊疗指南(2023年版)》,阿奇霉素用法:<span style='outline: 0px;background-color: transparent;caret-color: red;color: rgb(192, 0, 0);'><strong style='outline: 0px;'>轻症</strong></span>可予10mg/(kg·d),qd,口服或静点,疗程3d,必要时可延长至5d;轻症也可第一日10mg/(kg·d),qd,之后5mg/(kg·d),连用4天。</span></p><p style='outline: 0px;width: 647px;'><br style='outline: 0px;'></p><section style='padding-top: 5px;padding-bottom: 5px;outline: 0px;'><section data-autoskip="1" style='outline: 0px; line-height: 1.75em; letter-spacing: 1.5px; color: rgb(51, 51, 51); background-color: transparent;'><p style='outline: 0px;line-height: 2em;'><span style='outline: 0px;letter-spacing: 2px;color: rgb(192, 0, 0);font-family: Helvetica, Arial, sans-serif;'><strong style='outline: 0px;'><span style='outline: 0px;font-size: 16px;'>重症</span></strong></span><span style='outline: 0px;letter-spacing: 2px;color: rgb(38, 38, 38);font-family: Helvetica, Arial, sans-serif;'><span style='outline: 0px;'><strong style='outline: 0px;'><span style='outline: 0px;font-size: 16px;'></span></strong></span><span style='outline: 0px;font-size: 16px;'>推荐阿奇霉素静点,10mg/(kg·d),qd,连用7d左右,间隔3-4d后开始第2个疗程,总疗程依据病情而定,多为2-3个疗程,由静脉转换为口服给药的时机为患儿病情减轻、临床症状改善、体温正常时。 </span></span></p></section></section></section></section><section data-width="100%" style='outline: 0px;width: 677px;'><svg xmlns="http://www.w3.org/2000/svg" viewBox="0 0 579 26" style='display: block;'><path style='fill: #a0b1c5;fill-rule: evenodd;' d="M303,4717l579-1v26l-577.3-22.52Z" transform="translate(-303 -4716)"></path></svg></section></section></section><p style='outline: 0px; letter-spacing: 0.544px; font-family: system-ui, -apple-system, BlinkMacSystemFont, Arial, sans-serif;'><br></p><section data-tools="135编辑器" data-id="129095" style='outline: 0px; letter-spacing: 0.544px; font-family: system-ui, -apple-system, BlinkMacSystemFont, Arial, sans-serif;'><section style='margin: 10px auto;outline: 0px;'><section style='outline: 0px;background-color: rgb(244, 249, 255);'><section style='margin-bottom: 13px;outline: 0px;display: flex;justify-content: space-around;align-items: flex-start;'><section style='outline: 0px;'><section style='margin-left: 9px;outline: 0px;width: 5px;height: 10px;background-color: rgb(255, 255, 255);overflow: hidden;'><br style='outline: 0px;'></section><section style='margin-right: auto;margin-left: auto;outline: 0px;width: 18px;height: 6px;background-color: rgb(255, 255, 255);overflow: hidden;'><br style='outline: 0px;'></section></section><section style='outline: 0px;'><section style='margin-right: auto;margin-left: auto;outline: 0px;width: 5px;height: 10px;background-color: rgb(255, 255, 255);overflow: hidden;'><br style='outline: 0px;'></section><section style='margin-right: auto;margin-left: auto;outline: 0px;width: 15px;height: 6px;background-color: rgb(255, 255, 255);overflow: hidden;'><br style='outline: 0px;'></section></section><section style='outline: 0px;'><section style='margin-right: auto;margin-left: auto;outline: 0px;width: 5px;height: 10px;background-color: rgb(255, 255, 255);overflow: hidden;'><br style='outline: 0px;'></section><section style='margin-right: auto;margin-left: auto;outline: 0px;width: 15px;height: 6px;background-color: rgb(255, 255, 255);overflow: hidden;'><br style='outline: 0px;'></section></section><section style='outline: 0px;'><section style='margin-right: auto;margin-left: auto;outline: 0px;width: 5px;height: 10px;background-color: rgb(255, 255, 255);overflow: hidden;'><br style='outline: 0px;'></section><section style='margin-right: auto;margin-left: auto;outline: 0px;width: 15px;height: 6px;background-color: rgb(255, 255, 255);overflow: hidden;'><br style='outline: 0px;'></section></section><section style='outline: 0px;'><section style='margin-right: auto;margin-left: auto;outline: 0px;width: 5px;height: 10px;background-color: rgb(255, 255, 255);overflow: hidden;'><br style='outline: 0px;'></section><section style='margin-right: auto;margin-left: auto;outline: 0px;width: 15px;height: 6px;background-color: rgb(255, 255, 255);overflow: hidden;'><br style='outline: 0px;'></section></section><section style='outline: 0px;'><section style='margin-right: auto;margin-left: auto;outline: 0px;width: 5px;height: 10px;background-color: rgb(255, 255, 255);overflow: hidden;'><br style='outline: 0px;'></section><section style='margin-right: auto;margin-left: auto;outline: 0px;width: 15px;height: 6px;background-color: rgb(255, 255, 255);overflow: hidden;'><br style='outline: 0px;'></section></section><section style='outline: 0px;'><section style='margin-right: auto;margin-left: auto;outline: 0px;width: 5px;height: 10px;background-color: rgb(255, 255, 255);overflow: hidden;'><br style='outline: 0px;'></section><section style='margin-right: auto;margin-left: auto;outline: 0px;width: 15px;height: 6px;background-color: rgb(255, 255, 255);overflow: hidden;'><br style='outline: 0px;'></section></section><section style='outline: 0px;'><section style='margin-right: auto;margin-left: auto;outline: 0px;width: 5px;height: 10px;background-color: rgb(255, 255, 255);overflow: hidden;'><br style='outline: 0px;'></section><section style='margin-right: auto;margin-left: auto;outline: 0px;width: 15px;height: 6px;background-color: rgb(255, 255, 255);overflow: hidden;'><br style='outline: 0px;'></section></section><section style='outline: 0px;'><section style='margin-right: auto;margin-left: auto;outline: 0px;width: 5px;height: 10px;background-color: rgb(255, 255, 255);overflow: hidden;'><br style='outline: 0px;'></section><section style='margin-right: auto;margin-left: auto;outline: 0px;width: 15px;height: 6px;background-color: rgb(255, 255, 255);overflow: hidden;'><br style='outline: 0px;'></section></section><section style='outline: 0px;'><section style='margin-right: auto;margin-left: auto;outline: 0px;width: 5px;height: 10px;background-color: rgb(255, 255, 255);overflow: hidden;'><br style='outline: 0px;'></section><section style='margin-right: auto;margin-left: auto;outline: 0px;width: 15px;height: 6px;background-color: rgb(255, 255, 255);overflow: hidden;'><br style='outline: 0px;'></section></section><section style='outline: 0px;'><section style='margin-right: auto;margin-left: auto;outline: 0px;width: 5px;height: 10px;background-color: rgb(255, 255, 255);overflow: hidden;'><br style='outline: 0px;'></section><section style='margin-right: auto;margin-left: auto;outline: 0px;width: 15px;height: 6px;background-color: rgb(255, 255, 255);overflow: hidden;'><br style='outline: 0px;'></section></section><section style='outline: 0px;'><section style='margin-left: 5px;outline: 0px;width: 5px;height: 10px;background-color: rgb(255, 255, 255);overflow: hidden;'><br style='outline: 0px;'></section><section style='margin-right: auto;margin-left: auto;outline: 0px;width: 18px;height: 6px;background-color: rgb(255, 255, 255);overflow: hidden;'><br style='outline: 0px;'></section></section></section><section style='outline: 0px;display: flex;justify-content: center;'><section style='outline: 0px;display: flex;align-items: center;'><section style='outline: 0px;flex-shrink: 0;z-index: 9;transform: translateY(-3px);'><section style='outline: 0px;width: 40px;height: 0px;overflow: hidden;'><br style='outline: 0px;'></section></section><section style='margin-left: -30px;padding: 3px;outline: 0px;background-color: rgb(45, 150, 127);border-radius: 25px;'><p style='padding: 1px 20px 1px 35px;outline: 0px;text-align: center;color: rgb(255, 255, 255);font-size: 16px;border-width: 1px;border-style: solid;border-color: rgb(210, 227, 223);border-radius: 25px;background-color: rgb(27, 98, 176);'><span style='outline: 0px;'><strong data-brushtype="text" style='outline: 0px;'>为什么阿奇霉素用三天就停,</strong></span><strong data-brushtype="text" style='outline: 0px;letter-spacing: 0.544px;caret-color: red;'>不是直接吃七天呢?</strong></p></section></section></section><section style='padding: 8px 15px;outline: 0px;'><section data-width="100%" style='outline: 0px;width: 647px;'><br style='outline: 0px;'></section><section data-width="100%" style='outline: 0px;width: 647px;'><p style='outline: 0px;line-height: 2em;'><strong style='outline: 0px;letter-spacing: 0.544px;line-height: 2em;'><span style='outline: 0px;letter-spacing: 2px;background-color: transparent;caret-color: red;font-size: 16px;color: rgb(38, 38, 38);'>1.半衰期长:</span></strong><span style='outline: 0px;letter-spacing: 2px;background-color: transparent;caret-color: red;font-size: 16px;color: rgb(38, 38, 38);'>阿奇霉素单剂给药后的血消除半衰期为35-48小时。在组织半衰期更长,超过60小时。因此,</span><span style='outline: 0px;color: rgb(192, 0, 0);'><strong style='outline: 0px;'><span style='outline: 0px;letter-spacing: 2px;background-color: transparent;caret-color: red;font-size: 16px;'>服药3天后,即使停用,阿奇霉素依然能在体内持续作用3-4天。</span></strong></span></p></section><section data-width="100%" style='outline: 0px;width: 647px;'><p style='outline: 0px;background-color: transparent;color: rgb(51, 51, 51);letter-spacing: 1.5px;caret-color: red;font-size: 16px;'><br style='outline: 0px;'></p></section><section data-width="100%" style='outline: 0px;width: 647px;height: 0px;overflow: hidden;'><br style='outline: 0px;'></section><p style='outline: 0px;line-height: 2em;'><strong style='outline: 0px;letter-spacing: 0.544px;line-height: 2em;'><span style='outline: 0px;letter-spacing: 2px;background-color: transparent;caret-color: red;font-size: 16px;color: rgb(38, 38, 38);'>2.组织浓度高:</span></strong><span style='outline: 0px;font-size: 16px;letter-spacing: 2px;color: rgb(38, 38, 38);'>据研究,阿奇霉素的组织浓度较同期血药浓度高出10-100倍,炎症部位浓度比非炎症部位高达6倍以上,在巨噬细胞及纤维母细胞内浓度很高。</span></p><p style='outline: 0px;line-height: 2em;'><br style='outline: 0px;'></p><p style='outline: 0px;line-height: 2em;'><span style='outline: 0px;letter-spacing: 2px;color: rgb(38, 38, 38);'><span style='outline: 0px;font-size: 16px;'></span><span style='outline: 0px;font-size: 16px;font-family: mp-quote, -apple-system-font, BlinkMacSystemFont, Arial, sans-serif;'>服用阿奇霉素3-5天后第12天时白细胞及吞噬细胞内仍能测到一定浓度,10天后血清内仍有0.3-0.6μg/L。因而长时间使用,容易出现不良反应,所以,</span><span style='outline: 0px;color: rgb(192, 0, 0);'><strong style='outline: 0px;'><span style='outline: 0px;font-size: 16px;font-family: mp-quote, -apple-system-font, BlinkMacSystemFont, Arial, sans-serif;'>用3天,停4天可减少阿奇霉素的不良反应。</span></strong></span></span></p><p style='outline: 0px;line-height: 2em;'><br style='outline: 0px;'></p><p style='outline: 0px;line-height: 2em;'><strong style='outline: 0px;letter-spacing: 0.544px;line-height: 2em;'><span style='outline: 0px;letter-spacing: 2px;background-color: transparent;caret-color: red;font-size: 16px;color: rgb(38, 38, 38);'>3.存在抗生素后效应(PAE):</span></strong><span style='outline: 0px;font-size: 16px;letter-spacing: 2px;color: rgb(38, 38, 38);'>是指细菌与抗生素短暂接触后,药物浓度降至最低抑菌浓度以下或消除后细菌生长仍受持续抑制的效应。其产生的机制,一般认为是抗生素与细菌靶位持续性结合,引起细菌非致死性损伤或抗生素后促白细胞效应。</span></p><p style='outline: 0px;line-height: 2em;'><br style='outline: 0px;'></p><p style='outline: 0px;line-height: 2em;'><span style='outline: 0px;font-size: 16px;letter-spacing: 2px;color: rgb(38, 38, 38);'>阿奇霉素的抗菌活性呈现明显的PAE,其无论是高于或低于最低抑菌浓度时,均能促进吞噬细胞对金黄色葡萄球菌的调理吞噬作用,产生机制可能是药物与敏感核糖体亚基可逆性地结合抑制蛋白质的合成造成细菌非致死性损伤,而细菌恢复核糖体功能及恢复核蛋白质合成时间较长,故其PAE较长。</span></p></section></section><section data-width="100%" style='outline: 0px;width: 677px;'><svg xmlns="http://www.w3.org/2000/svg" viewBox="0 0 579 26" style='display: block;'><path style='fill: #a0b1c5;fill-rule: evenodd;' d="M303,4717l579-1v26l-577.3-22.52Z" transform="translate(-303 -4716)"></path></svg></section></section></section><section data-role="paragraph" style='outline: 0px; letter-spacing: 0.544px; font-family: system-ui, -apple-system, BlinkMacSystemFont, Arial, sans-serif;'><section style='letter-spacing: 0.578px; line-height: 1.75em;'><br></section><section data-tools="135编辑器" data-id="129095" style='letter-spacing: 0.544px; outline: 0px;'><section style='margin: 10px auto;outline: 0px;'><section style='outline: 0px;background-color: rgb(244, 249, 255);'><section style='margin-bottom: 13px;outline: 0px;display: flex;justify-content: space-around;align-items: flex-start;'><section style='outline: 0px;'><section style='margin-left: 9px;outline: 0px;width: 5px;height: 10px;background-color: rgb(255, 255, 255);overflow: hidden;'><br style='outline: 0px;'></section><section style='margin-right: auto;margin-left: auto;outline: 0px;width: 18px;height: 6px;background-color: rgb(255, 255, 255);overflow: hidden;'><br style='outline: 0px;'></section></section><section style='outline: 0px;'><section style='margin-right: auto;margin-left: auto;outline: 0px;width: 5px;height: 10px;background-color: rgb(255, 255, 255);overflow: hidden;'><br style='outline: 0px;'></section><section style='margin-right: auto;margin-left: auto;outline: 0px;width: 15px;height: 6px;background-color: rgb(255, 255, 255);overflow: hidden;'><br style='outline: 0px;'></section></section><section style='outline: 0px;'><section style='margin-right: auto;margin-left: auto;outline: 0px;width: 5px;height: 10px;background-color: rgb(255, 255, 255);overflow: hidden;'><br style='outline: 0px;'></section><section style='margin-right: auto;margin-left: auto;outline: 0px;width: 15px;height: 6px;background-color: rgb(255, 255, 255);overflow: hidden;'><br style='outline: 0px;'></section></section><section style='outline: 0px;'><section style='margin-right: auto;margin-left: auto;outline: 0px;width: 5px;height: 10px;background-color: rgb(255, 255, 255);overflow: hidden;'><br style='outline: 0px;'></section><section style='margin-right: auto;margin-left: auto;outline: 0px;width: 15px;height: 6px;background-color: rgb(255, 255, 255);overflow: hidden;'><br style='outline: 0px;'></section></section><section style='outline: 0px;'><section style='margin-right: auto;margin-left: auto;outline: 0px;width: 5px;height: 10px;background-color: rgb(255, 255, 255);overflow: hidden;'><br style='outline: 0px;'></section><section style='margin-right: auto;margin-left: auto;outline: 0px;width: 15px;height: 6px;background-color: rgb(255, 255, 255);overflow: hidden;'><br style='outline: 0px;'></section></section><section style='outline: 0px;'><section style='margin-right: auto;margin-left: auto;outline: 0px;width: 5px;height: 10px;background-color: rgb(255, 255, 255);overflow: hidden;'><br style='outline: 0px;'></section><section style='margin-right: auto;margin-left: auto;outline: 0px;width: 15px;height: 6px;background-color: rgb(255, 255, 255);overflow: hidden;'><br style='outline: 0px;'></section></section><section style='outline: 0px;'><section style='margin-right: auto;margin-left: auto;outline: 0px;width: 5px;height: 10px;background-color: rgb(255, 255, 255);overflow: hidden;'><br style='outline: 0px;'></section><section style='margin-right: auto;margin-left: auto;outline: 0px;width: 15px;height: 6px;background-color: rgb(255, 255, 255);overflow: hidden;'><br style='outline: 0px;'></section></section><section style='outline: 0px;'><section style='margin-right: auto;margin-left: auto;outline: 0px;width: 5px;height: 10px;background-color: rgb(255, 255, 255);overflow: hidden;'><br style='outline: 0px;'></section><section style='margin-right: auto;margin-left: auto;outline: 0px;width: 15px;height: 6px;background-color: rgb(255, 255, 255);overflow: hidden;'><br style='outline: 0px;'></section></section><section style='outline: 0px;'><section style='margin-right: auto;margin-left: auto;outline: 0px;width: 5px;height: 10px;background-color: rgb(255, 255, 255);overflow: hidden;'><br style='outline: 0px;'></section><section style='margin-right: auto;margin-left: auto;outline: 0px;width: 15px;height: 6px;background-color: rgb(255, 255, 255);overflow: hidden;'><br style='outline: 0px;'></section></section><section style='outline: 0px;'><section style='margin-right: auto;margin-left: auto;outline: 0px;width: 5px;height: 10px;background-color: rgb(255, 255, 255);overflow: hidden;'><br style='outline: 0px;'></section><section style='margin-right: auto;margin-left: auto;outline: 0px;width: 15px;height: 6px;background-color: rgb(255, 255, 255);overflow: hidden;'><br style='outline: 0px;'></section></section><section style='outline: 0px;'><section style='margin-right: auto;margin-left: auto;outline: 0px;width: 5px;height: 10px;background-color: rgb(255, 255, 255);overflow: hidden;'><br style='outline: 0px;'></section><section style='margin-right: auto;margin-left: auto;outline: 0px;width: 15px;height: 6px;background-color: rgb(255, 255, 255);overflow: hidden;'><br style='outline: 0px;'></section></section><section style='outline: 0px;'><section style='margin-left: 5px;outline: 0px;width: 5px;height: 10px;background-color: rgb(255, 255, 255);overflow: hidden;'><br style='outline: 0px;'></section><section style='margin-right: auto;margin-left: auto;outline: 0px;width: 18px;height: 6px;background-color: rgb(255, 255, 255);overflow: hidden;'><br style='outline: 0px;'></section></section></section><section style='outline: 0px;display: flex;justify-content: center;'><section style='outline: 0px;display: flex;align-items: center;'><section style='outline: 0px;flex-shrink: 0;z-index: 9;transform: translateY(-3px);'><section style='outline: 0px;width: 40px;height: 0px;overflow: hidden;'><br style='outline: 0px;'></section></section><section style='margin-left: -30px;padding: 3px;outline: 0px;background-color: rgb(45, 150, 127);border-radius: 25px;'><p style='padding: 1px 20px 1px 35px;outline: 0px;text-align: center;color: rgb(255, 255, 255);font-size: 16px;border-width: 1px;border-style: solid;border-color: rgb(210, 227, 223);border-radius: 25px;background-color: rgb(27, 98, 176);'><strong>国产、进口阿奇霉素效果有差别吗?</strong><strong data-brushtype="text" style='outline: 0px;letter-spacing: 0.544px;caret-color: red;'></strong></p></section></section></section><section style='padding: 8px 15px;outline: 0px;'><section data-width="100%" style='outline: 0px;width: 647px;'><br style='outline: 0px;'></section><section data-width="100%" style='outline: 0px;width: 647px;'><p><span style='letter-spacing: 1px;'>目前治疗的药物基本国产化,尤其阿奇霉素,</span><strong>效果和国外进口基本一致。</strong></p><p style='letter-spacing: 0.578px;line-height: 1.75em;'><span style='font-size: 16px;letter-spacing: 2px;'></span></p></section></section></section><section data-width="100%" style='outline: 0px;width: 677px;'><svg xmlns="http://www.w3.org/2000/svg" viewBox="0 0 579 26" style='display: block;'><path style='fill: #a0b1c5;fill-rule: evenodd;' d="M303,4717l579-1v26l-577.3-22.52Z" transform="translate(-303 -4716)"></path></svg></section></section></section><section data-role="paragraph" style='letter-spacing: 0.544px; outline: 0px;'><section style='letter-spacing: 0.578px;line-height: 1.75em;'><br></section></section><section data-tools="135编辑器" data-id="129095" style='outline: 0px; letter-spacing: 0.544px;'><section style='margin: 10px auto;outline: 0px;'><section style='outline: 0px;background-color: rgb(244, 249, 255);'><section style='margin-bottom: 13px;outline: 0px;display: flex;justify-content: space-around;align-items: flex-start;'><section style='outline: 0px;'><section style='margin-left: 9px;outline: 0px;width: 5px;height: 10px;background-color: rgb(255, 255, 255);overflow: hidden;'><br style='outline: 0px;'></section><section style='margin-right: auto;margin-left: auto;outline: 0px;width: 18px;height: 6px;background-color: rgb(255, 255, 255);overflow: hidden;'><br style='outline: 0px;'></section></section><section style='outline: 0px;'><section style='margin-right: auto;margin-left: auto;outline: 0px;width: 5px;height: 10px;background-color: rgb(255, 255, 255);overflow: hidden;'><br style='outline: 0px;'></section><section style='margin-right: auto;margin-left: auto;outline: 0px;width: 15px;height: 6px;background-color: rgb(255, 255, 255);overflow: hidden;'><br style='outline: 0px;'></section></section><section style='outline: 0px;'><section style='margin-right: auto;margin-left: auto;outline: 0px;width: 5px;height: 10px;background-color: rgb(255, 255, 255);overflow: hidden;'><br style='outline: 0px;'></section><section style='margin-right: auto;margin-left: auto;outline: 0px;width: 15px;height: 6px;background-color: rgb(255, 255, 255);overflow: hidden;'><br style='outline: 0px;'></section></section><section style='outline: 0px;'><section style='margin-right: auto;margin-left: auto;outline: 0px;width: 5px;height: 10px;background-color: rgb(255, 255, 255);overflow: hidden;'><br style='outline: 0px;'></section><section style='margin-right: auto;margin-left: auto;outline: 0px;width: 15px;height: 6px;background-color: rgb(255, 255, 255);overflow: hidden;'><br style='outline: 0px;'></section></section><section style='outline: 0px;'><section style='margin-right: auto;margin-left: auto;outline: 0px;width: 5px;height: 10px;background-color: rgb(255, 255, 255);overflow: hidden;'><br style='outline: 0px;'></section><section style='margin-right: auto;margin-left: auto;outline: 0px;width: 15px;height: 6px;background-color: rgb(255, 255, 255);overflow: hidden;'><br style='outline: 0px;'></section></section><section style='outline: 0px;'><section style='margin-right: auto;margin-left: auto;outline: 0px;width: 5px;height: 10px;background-color: rgb(255, 255, 255);overflow: hidden;'><br style='outline: 0px;'></section><section style='margin-right: auto;margin-left: auto;outline: 0px;width: 15px;height: 6px;background-color: rgb(255, 255, 255);overflow: hidden;'><br style='outline: 0px;'></section></section><section style='outline: 0px;'><section style='margin-right: auto;margin-left: auto;outline: 0px;width: 5px;height: 10px;background-color: rgb(255, 255, 255);overflow: hidden;'><br style='outline: 0px;'></section><section style='margin-right: auto;margin-left: auto;outline: 0px;width: 15px;height: 6px;background-color: rgb(255, 255, 255);overflow: hidden;'><br style='outline: 0px;'></section></section><section style='outline: 0px;'><section style='margin-right: auto;margin-left: auto;outline: 0px;width: 5px;height: 10px;background-color: rgb(255, 255, 255);overflow: hidden;'><br style='outline: 0px;'></section><section style='margin-right: auto;margin-left: auto;outline: 0px;width: 15px;height: 6px;background-color: rgb(255, 255, 255);overflow: hidden;'><br style='outline: 0px;'></section></section><section style='outline: 0px;'><section style='margin-right: auto;margin-left: auto;outline: 0px;width: 5px;height: 10px;background-color: rgb(255, 255, 255);overflow: hidden;'><br style='outline: 0px;'></section><section style='margin-right: auto;margin-left: auto;outline: 0px;width: 15px;height: 6px;background-color: rgb(255, 255, 255);overflow: hidden;'><br style='outline: 0px;'></section></section><section style='outline: 0px;'><section style='margin-right: auto;margin-left: auto;outline: 0px;width: 5px;height: 10px;background-color: rgb(255, 255, 255);overflow: hidden;'><br style='outline: 0px;'></section><section style='margin-right: auto;margin-left: auto;outline: 0px;width: 15px;height: 6px;background-color: rgb(255, 255, 255);overflow: hidden;'><br style='outline: 0px;'></section></section><section style='outline: 0px;'><section style='margin-right: auto;margin-left: auto;outline: 0px;width: 5px;height: 10px;background-color: rgb(255, 255, 255);overflow: hidden;'><br style='outline: 0px;'></section><section style='margin-right: auto;margin-left: auto;outline: 0px;width: 15px;height: 6px;background-color: rgb(255, 255, 255);overflow: hidden;'><br style='outline: 0px;'></section></section><section style='outline: 0px;'><section style='margin-left: 5px;outline: 0px;width: 5px;height: 10px;background-color: rgb(255, 255, 255);overflow: hidden;'><br style='outline: 0px;'></section><section style='margin-right: auto;margin-left: auto;outline: 0px;width: 18px;height: 6px;background-color: rgb(255, 255, 255);overflow: hidden;'><br style='outline: 0px;'></section></section></section><section style='outline: 0px;display: flex;justify-content: center;'><section style='outline: 0px;display: flex;align-items: center;'><section style='outline: 0px;flex-shrink: 0;z-index: 9;transform: translateY(-3px);'><section style='outline: 0px;width: 40px;height: 0px;overflow: hidden;'><br style='outline: 0px;'></section></section><section style='margin-left: -30px;padding: 3px;outline: 0px;background-color: rgb(45, 150, 127);border-radius: 25px;'><p style='padding: 1px 20px 1px 35px;outline: 0px;text-align: center;color: rgb(255, 255, 255);font-size: 16px;border-width: 1px;border-style: solid;border-color: rgb(210, 227, 223);border-radius: 25px;background-color: rgb(27, 98, 176);'><strong>一旦出现耐药,有无替代药物?</strong><strong data-brushtype="text" style='outline: 0px;letter-spacing: 0.544px;caret-color: red;'></strong></p></section></section></section><section style='padding: 8px 15px;outline: 0px;'><section data-width="100%" style='outline: 0px;width: 647px;'><br style='outline: 0px;'></section><section data-width="100%" style='outline: 0px;width: 647px;'><p style='letter-spacing: 0.578px; line-height: 1.75em;'><span style='font-size: 16px;letter-spacing: 2px;'>肺炎支原体感染患者如果对大环内酯类药物出现耐药,有两类替代性药物。</span></p><p style='letter-spacing: 0.578px; line-height: 1.75em;'><span style='font-size: 16px;letter-spacing: 2px;'><br></span></p><p style='letter-spacing: 0.578px; line-height: 1.75em;'><span style='font-size: 16px;letter-spacing: 2px;'>一类是<strong>新型四环素类抗菌药物</strong><strong>,主要包括多西环素和米诺环素</strong>。对耐药肺炎支原体肺炎有确切疗效。由于可能导致牙齿发黄和牙釉质发育不良,仅适用于8岁以上儿童。8岁以下儿童属于超说明书用药。米诺环素的作用相对较强,多西环素的安全性较高,在推荐剂量和疗程内,尚无持久牙齿黄染的报道。</span></p><p style='letter-spacing: 0.578px; line-height: 1.75em;'><span style='font-size: 16px;letter-spacing: 2px;'><br></span></p><p style='letter-spacing: 0.578px; line-height: 1.75em;'><span style='font-size: 16px;letter-spacing: 2px;'>另一类替代药物为<strong>喹诺酮类药物,常用的为左氧氟沙星、环丙沙星、莫西沙星等</strong>,由于存在骨骼肌腱方面的潜在风险,我国18岁以下儿童使用属超说明书用药。临床上,大环内酯类药物仍作为一线药物推荐使用,但存在耐药时,亦可根据病情选用四环素及喹诺酮类药物。</span></p><p style='outline: 0px;line-height: 2em;'><br></p></section><p style='outline: 0px;line-height: 2em;'><br></p></section></section><section data-width="100%" style='outline: 0px;width: 677px;'><svg xmlns="http://www.w3.org/2000/svg" viewBox="0 0 579 26" style='display: block;'><path style='fill: #a0b1c5;fill-rule: evenodd;' d="M303,4717l579-1v26l-577.3-22.52Z" transform="translate(-303 -4716)"></path></svg></section></section></section><section data-role="paragraph" style='outline: 0px; letter-spacing: 0.544px;'><section style='letter-spacing: 0.578px;line-height: 1.75em;'><br></section></section></section><section data-tools="135编辑器" data-id="121441" style='outline: 0px; letter-spacing: 0.544px; font-family: system-ui, -apple-system, BlinkMacSystemFont, Arial, sans-serif;'><section style='margin: 10px auto;outline: 0px;transform-style: preserve-3d;'><section style='margin-bottom: -15px;padding-left: 10px;outline: 0px;display: flex;justify-content: flex-start;transform: translateZ(10px);'><section style='outline: 0px; color: rgb(255, 255, 255); width: 28px; height: 28px; line-height: 28px; text-align: center; border-radius: 100%; background-color: rgb(243, 199, 102);'><strong style='outline: 0px;'><span style='outline: 0px;font-size: 16px;'>药</span></strong></section><section style='outline: 0px; color: rgb(255, 255, 255); width: 28px; height: 28px; line-height: 28px; text-align: center; border-radius: 100%; background-color: rgb(192, 0, 0);'><strong style='outline: 0px;'><span style='outline: 0px;font-size: 16px;'>师<br style='outline: 0px;'></span></strong></section><section style='outline: 0px; color: rgb(255, 255, 255); width: 28px; height: 28px; line-height: 28px; text-align: center; border-radius: 100%; background-color: rgb(243, 199, 102);'><strong style='outline: 0px;'><span style='outline: 0px;font-size: 16px;'>提</span></strong></section><section style='outline: 0px; color: rgb(255, 255, 255); width: 28px; height: 28px; line-height: 28px; text-align: center; border-radius: 100%; background-color: rgb(192, 0, 0);'><strong style='outline: 0px;'><span style='outline: 0px;font-size: 16px;'>醒</span></strong><span style='outline: 0px;font-size: 16px;'><br style='outline: 0px;'></span></section></section><section style='padding: 25px 15px 15px;outline: 0px;border-width: 1px;border-style: solid;border-color: rgb(192, 0, 0);border-radius: 8px;transform: translateZ(5px);'><section data-autoskip="1" style='outline: 0px; line-height: 1.75em; letter-spacing: 1.5px; color: rgb(51, 51, 51); background-position: initial; background-size: initial; background-repeat: initial; background-attachment: initial; background-origin: initial; background-clip: initial;'><p style='outline: 0px;vertical-align: inherit;'><br style='outline: 0px;'></p><section style='outline: 0px;vertical-align: inherit;text-indent: 2em;line-height: 2em;'><section style='outline: 0px;line-height: 2em;text-indent: 0em;'><span style='outline: 0px;letter-spacing: 2px;'><span style='outline: 0px;text-indent: 0em;font-size: 16px;text-decoration-style: solid;text-decoration-color: rgb(51, 51, 51);font-family: mp-quote, -apple-system-font, BlinkMacSystemFont, Arial, sans-serif;'>肺炎支原体感染主要是经过飞沫传播,目前,</span><span style='outline: 0px;color: rgb(192, 0, 0);'><strong style='outline: 0px;'><span style='outline: 0px;text-indent: 0em;font-size: 16px;text-decoration-style: solid;text-decoration-color: rgb(51, 51, 51);font-family: mp-quote, -apple-system-font, BlinkMacSystemFont, Arial, sans-serif;'>还没有针对肺炎支原体感染的疫苗。</span></strong></span><span style='outline: 0px;text-indent: 0em;font-size: 16px;font-family: mp-quote, -apple-system-font, BlinkMacSystemFont, Arial, sans-serif;'>建议低龄儿童、免疫功能低下的老年人应尽量避免到人群密集和通风不良的公共场所,必须去时应戴好口罩,同时保持勤洗手、勤通风等良好的卫生习惯。</span></span></section></section><section style='outline: 0px;vertical-align: inherit;text-indent: 2em;line-height: 2em;'><section style='outline: 0px;font-size: 16px;font-family: mp-quote, -apple-system-font, BlinkMacSystemFont, Arial, sans-serif;text-indent: 0em;'><br style='outline: 0px;'></section></section><section style='outline: 0px;vertical-align: inherit;text-indent: 2em;line-height: 2em;'><section style='outline: 0px;line-height: 2em;text-indent: 0em;'><span style='outline: 0px;text-indent: 0em;font-size: 16px;letter-spacing: 2px;font-family: mp-quote, -apple-system-font, BlinkMacSystemFont, Arial, sans-serif;'>若出现高烧反复不退、精神差,在使用一般的感冒药或者消炎药后,症状无好转,反而有加重趋势,即使没有咳嗽或咳嗽较少,也</span><span style='outline: 0px;color: rgb(192, 0, 0);'><strong style='outline: 0px;'><span style='outline: 0px;text-indent: 0em;font-size: 16px;letter-spacing: 2px;font-family: mp-quote, -apple-system-font, BlinkMacSystemFont, Arial, sans-serif;'>建议去医院看诊</span></strong></span><span style='outline: 0px;text-indent: 0em;font-size: 16px;letter-spacing: 2px;font-family: mp-quote, -apple-system-font, BlinkMacSystemFont, Arial, sans-serif;'>,并结合临床和影像学表现以及病原学、血清学检查来进行判断,<span style='outline: 0px;'>尽快查明病因,规范治疗,切忌自行盲目用药,不规范的混搭用药可能引发严重的后果,甚至会导致死亡。</span></span></section></section></section></section></section></section><p style='outline: 0px; font-family: system-ui, -apple-system, BlinkMacSystemFont, Arial, sans-serif; letter-spacing: 0.544px; font-size: 16px; color: rgb(0, 0, 0);'><br style='outline: 0px;'></p><section powered-by="xiumi.us" style='outline: 0px; font-family: system-ui, -apple-system, BlinkMacSystemFont, Arial, sans-serif; letter-spacing: 0.544px; font-size: 16px; color: rgb(4, 4, 4);'><section style='outline: 0px;letter-spacing: 0.544px;color: rgb(0, 0, 0);text-align: center;widows: 1;caret-color: rgb(34, 34, 34);'><section data-id="135149" data-type="lspecial04" powered-by="xmyeditor.com" data-md5="a7689" act="xmy" style='outline: 0px;'><section powered-by="xmyeditor.com" data-md5="a7689" style='outline: 0px;'><section powered-by="xmyeditor.com" data-md5="a7689" style='outline: 0px;'><section powered-by="xmyeditor.com" data-md5="a7689" style='outline: 0px;'><section data-md5="a7689" powered-by="xmyeditor.com" style='outline: 0px;'><section powered-by="xmyeditor.com" data-md5="a7689" style='outline: 0px;'><section powered-by="xiumi.us" style='margin-bottom: 0em;outline: 0px;letter-spacing: 0.544px;visibility: visible;'><br></section><section powered-by="xiumi.us" style='outline: 0px;letter-spacing: 0.544px;'><section data-role="outer" label="edit by 135editor" style='outline: 0px;letter-spacing: 0.544px;color: rgb(36, 79, 113);'><h2 data-darkmode-bgcolor-16475014263612="rgb(25, 25, 25)" data-darkmode-original-bgcolor-16475014263612="#fff|rgb(255, 255, 255)|rgb(255, 255, 255)" data-darkmode-color-16475014263612="rgb(163, 163, 163)" data-darkmode-original-color-16475014263612="#fff|rgb(0, 0, 0)" data-style='white-space: normal; outline: 0px; max-width: 100%; letter-spacing: 0.544px; background-color: rgb(255, 255, 255); widows: 1; text-align: right; color: rgb(0, 0, 0); font-family: -apple-system-font, BlinkMacSystemFont, Arial, sans-serif; box-sizing: border-box !important; overflow-wrap: break-word !important;' class="js_darkmode__26" style='outline: 0px;'><pre style='outline: currentcolor none 0px;caret-color: rgba(0, 0, 0, 0);visibility: visible;'><section data-role="paragraph" style='outline: 0px;white-space: normal;visibility: visible;'><section style='outline: 0px;line-height: 1.75;visibility: visible;'><section powered-by="xiumi.us" style='outline: 0px;visibility: visible;'><section style='outline: 0px;line-height: 1.75;visibility: visible;'><section powered-by="xiumi.us" style='outline: 0px;visibility: visible;'><section data-source="bj.96weixin.com" mp-original-font-size="16" mp-original-line-height="25.600000381469727" style='margin-bottom: 24px;outline: 0px;visibility: visible;'><section data-role="paragraph" style='margin-bottom: 0em;outline: 0px;visibility: visible;'><section data-role="paragraph" style='outline: 0px;'><section data-role="paragraph" style='margin-bottom: 0em;outline: 0px;font-family: -apple-system, BlinkMacSystemFont, Arial, sans-serif;letter-spacing: 0.544px;color: rgb(34, 34, 34);visibility: visible;line-height: 1.75;'><section style='margin-bottom: 0em;outline: 0px;letter-spacing: 0.544px;visibility: visible;line-height: 1.75;'><br data-filtered="filtered" style='outline: 0px;'></section></section><p style='outline: 0px;text-align: left;color: rgb(34, 34, 34);visibility: visible;line-height: 1.75;'><span style='margin-bottom: 0em;outline: 0px;font-family: "Helvetica Neue", Helvetica, Arial, sans-serif;letter-spacing: normal;font-size: 14px;color: rgb(136, 136, 136);'>来源</span><span style='margin-bottom: 0em;outline: 0px;font-family: "Helvetica Neue", Helvetica, Arial, sans-serif;letter-spacing: normal;font-size: 14px;color: rgb(136, 136, 136);'>:湖北发</span><span style='margin-bottom: 0em;outline: 0px;font-family: "Helvetica Neue", Helvetica, Arial, sans-serif;letter-spacing: normal;font-size: 14px;color: rgb(136, 136, 136);'>布</span><span style='margin-bottom: 0em;outline: 0px;font-family: "Helvetica Neue", Helvetica, Arial, sans-serif;letter-spacing: normal;font-size: 14px;color: rgb(136, 136, 136);'>、央视网、央视新闻客户端、“湖北药监”微信公众号、长江云新闻</span></p><section style='outline: 0px;text-align: left;color: rgb(34, 34, 34);visibility: visible;line-height: 1.75;'><br></section></section></section></section></section></section></section></section></section></pre></h2></section></section></section></section></section></section></section></section></section></section></div>
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